ComTalk (2004)
This was a fun application I wrote several years ago when became interested in speech synthesis technology. Harnessing the power of Microsoft's MSAgent technology, ComTalk can read out text for you, tell you the time, open applications in response to your voice and much more.
ComTalk's source code is largely a mess, having being written when my OO programming knowledge was underdeveloped. Nevertheless it may serve as an example of VB6 driving the Microsoft MSAgent component.